The Healthy Buildings LLC Certification System Software Platform and subsequent effective and efficient implementation adds value for various stakeholders who are involved with optimizing this human-building-environment interface, such as employers, employees, property owners, tenants, patients, clinicians, and policymakers. For tenants, patients, and employees, enhancing the healthy building determinant – MSD domain through our Certification System and implementation could result in improved quality of life, function, and productivity. For employers, these enhancements could improve measures related to job performance and employee retention. For property owners, upgrades to human-building-environment interface within the HBD-MSD domain could result in financial gains, such as higher rental fees and enhanced tenant satisfaction and retention. For policymakers, as well as organizations with ecological, social, and governance missions, implementation of practices to optimize the HBD-MSD domain can have wide ranging impact on reducing human disability related to the built environment